Review



human nsclc tissue array  (Novus Biologicals)


Bioz Verified Symbol Novus Biologicals is a verified supplier
Bioz Manufacturer Symbol Novus Biologicals manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Novus Biologicals human nsclc tissue array
    HDAC11 expression in human lung tumor tissues and cells and its correlation with patient prognosis. ( A ) Elevated HDAC11 staining is seen in <t>NSCLC</t> <t>tissue</t> and its metastatic sites as compared to the normal human lung tissue in TMA. ( B ) Quantitation of IHC performed on the TMA shows a ~2.5–3-fold increase in HDAC11 expression in human lung adenocarcinoma tissue, squamous cell carcinoma (SCC) and metastatic lung carcinoma as compared to normal lung tissue. ( C ) Quantitation of second IHC staining for HDAC11 also showed 3-fold increase in HDAC11 expression in NSCLC patient tumor tissue as compared to normal lung tissue. ( D , E ) Kaplan-Meier survival analysis for HDAC11 (Probeset 219847_at) shows poor prognosis in lung adenocarcinoma ( D ) and squamous cell carcinoma ( E ) patients with higher mRNA expression of HDAC11 in them. ( F ) HDAC11 could be detected in multiple cell lines of different histology by a western blot analysis. Similarly, Sox2 and YAP1 could also be detected in these cells. The images of the full scan western blots are provided in Supplementary Fig. .
    Human Nsclc Tissue Array, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human nsclc tissue array/product/Novus Biologicals
    Average 90 stars, based on 9 article reviews
    human nsclc tissue array - by Bioz Stars, 2026-05
    90/100 stars

    Images

    1) Product Images from "Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2"

    Article Title: Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2

    Journal: Scientific Reports

    doi: 10.1038/s41598-020-61295-6

    HDAC11 expression in human lung tumor tissues and cells and its correlation with patient prognosis. ( A ) Elevated HDAC11 staining is seen in NSCLC tissue and its metastatic sites as compared to the normal human lung tissue in TMA. ( B ) Quantitation of IHC performed on the TMA shows a ~2.5–3-fold increase in HDAC11 expression in human lung adenocarcinoma tissue, squamous cell carcinoma (SCC) and metastatic lung carcinoma as compared to normal lung tissue. ( C ) Quantitation of second IHC staining for HDAC11 also showed 3-fold increase in HDAC11 expression in NSCLC patient tumor tissue as compared to normal lung tissue. ( D , E ) Kaplan-Meier survival analysis for HDAC11 (Probeset 219847_at) shows poor prognosis in lung adenocarcinoma ( D ) and squamous cell carcinoma ( E ) patients with higher mRNA expression of HDAC11 in them. ( F ) HDAC11 could be detected in multiple cell lines of different histology by a western blot analysis. Similarly, Sox2 and YAP1 could also be detected in these cells. The images of the full scan western blots are provided in Supplementary Fig. .
    Figure Legend Snippet: HDAC11 expression in human lung tumor tissues and cells and its correlation with patient prognosis. ( A ) Elevated HDAC11 staining is seen in NSCLC tissue and its metastatic sites as compared to the normal human lung tissue in TMA. ( B ) Quantitation of IHC performed on the TMA shows a ~2.5–3-fold increase in HDAC11 expression in human lung adenocarcinoma tissue, squamous cell carcinoma (SCC) and metastatic lung carcinoma as compared to normal lung tissue. ( C ) Quantitation of second IHC staining for HDAC11 also showed 3-fold increase in HDAC11 expression in NSCLC patient tumor tissue as compared to normal lung tissue. ( D , E ) Kaplan-Meier survival analysis for HDAC11 (Probeset 219847_at) shows poor prognosis in lung adenocarcinoma ( D ) and squamous cell carcinoma ( E ) patients with higher mRNA expression of HDAC11 in them. ( F ) HDAC11 could be detected in multiple cell lines of different histology by a western blot analysis. Similarly, Sox2 and YAP1 could also be detected in these cells. The images of the full scan western blots are provided in Supplementary Fig. .

    Techniques Used: Expressing, Staining, Quantitation Assay, Immunohistochemistry, Western Blot



    Similar Products

    human nsclc tissue array  (Novus Biologicals)
    90
    Novus Biologicals human nsclc tissue array
    HDAC11 expression in human lung tumor tissues and cells and its correlation with patient prognosis. ( A ) Elevated HDAC11 staining is seen in <t>NSCLC</t> <t>tissue</t> and its metastatic sites as compared to the normal human lung tissue in TMA. ( B ) Quantitation of IHC performed on the TMA shows a ~2.5–3-fold increase in HDAC11 expression in human lung adenocarcinoma tissue, squamous cell carcinoma (SCC) and metastatic lung carcinoma as compared to normal lung tissue. ( C ) Quantitation of second IHC staining for HDAC11 also showed 3-fold increase in HDAC11 expression in NSCLC patient tumor tissue as compared to normal lung tissue. ( D , E ) Kaplan-Meier survival analysis for HDAC11 (Probeset 219847_at) shows poor prognosis in lung adenocarcinoma ( D ) and squamous cell carcinoma ( E ) patients with higher mRNA expression of HDAC11 in them. ( F ) HDAC11 could be detected in multiple cell lines of different histology by a western blot analysis. Similarly, Sox2 and YAP1 could also be detected in these cells. The images of the full scan western blots are provided in Supplementary Fig. .
    Human Nsclc Tissue Array, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human nsclc tissue array/product/Novus Biologicals
    Average 90 stars, based on 1 article reviews
    human nsclc tissue array - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    HDAC11 expression in human lung tumor tissues and cells and its correlation with patient prognosis. ( A ) Elevated HDAC11 staining is seen in NSCLC tissue and its metastatic sites as compared to the normal human lung tissue in TMA. ( B ) Quantitation of IHC performed on the TMA shows a ~2.5–3-fold increase in HDAC11 expression in human lung adenocarcinoma tissue, squamous cell carcinoma (SCC) and metastatic lung carcinoma as compared to normal lung tissue. ( C ) Quantitation of second IHC staining for HDAC11 also showed 3-fold increase in HDAC11 expression in NSCLC patient tumor tissue as compared to normal lung tissue. ( D , E ) Kaplan-Meier survival analysis for HDAC11 (Probeset 219847_at) shows poor prognosis in lung adenocarcinoma ( D ) and squamous cell carcinoma ( E ) patients with higher mRNA expression of HDAC11 in them. ( F ) HDAC11 could be detected in multiple cell lines of different histology by a western blot analysis. Similarly, Sox2 and YAP1 could also be detected in these cells. The images of the full scan western blots are provided in Supplementary Fig. .

    Journal: Scientific Reports

    Article Title: Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2

    doi: 10.1038/s41598-020-61295-6

    Figure Lengend Snippet: HDAC11 expression in human lung tumor tissues and cells and its correlation with patient prognosis. ( A ) Elevated HDAC11 staining is seen in NSCLC tissue and its metastatic sites as compared to the normal human lung tissue in TMA. ( B ) Quantitation of IHC performed on the TMA shows a ~2.5–3-fold increase in HDAC11 expression in human lung adenocarcinoma tissue, squamous cell carcinoma (SCC) and metastatic lung carcinoma as compared to normal lung tissue. ( C ) Quantitation of second IHC staining for HDAC11 also showed 3-fold increase in HDAC11 expression in NSCLC patient tumor tissue as compared to normal lung tissue. ( D , E ) Kaplan-Meier survival analysis for HDAC11 (Probeset 219847_at) shows poor prognosis in lung adenocarcinoma ( D ) and squamous cell carcinoma ( E ) patients with higher mRNA expression of HDAC11 in them. ( F ) HDAC11 could be detected in multiple cell lines of different histology by a western blot analysis. Similarly, Sox2 and YAP1 could also be detected in these cells. The images of the full scan western blots are provided in Supplementary Fig. .

    Article Snippet: Human NSCLC tissue array (NBP2-30222, Novus Biologicals) had 59 cores including normal lung (9 cores), NSCLCs (40 cores) and metastatic NSCLCs (10 cores).

    Techniques: Expressing, Staining, Quantitation Assay, Immunohistochemistry, Western Blot